Home  |  Top News  |  Most Popular  |  Video  |  Multimedia  |  News Feeds  |  Feedback
  Medicine  |  Nature & Earth  |  Biology  |  Technology & Engineering  |  Space & Planetary  |  Psychology  |  Physics & Chemistry  |  Economics  |  Archaeology
Top > Medicine, Health Care > Simple Ultrasound Treatment May Help… >

Simple Ultrasound Treatment May Help Protect the Kidneys

Published: August 1, 2013.
Released by American Society of Nephrology  

Washington, DC (August 1, 2013) — Ultrasound treatments may prevent acute kidney injury that commonly arises after major surgery, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings suggest that this simple and noninvasive therapy may be an effective precaution for patients at risk.

Acute kidney injury, an abrupt decline in kidney function, is an increasingly prevalent and potentially serious condition in hospitalized patients. Sometimes acute kidney injury arises after major surgery because the kidneys can be deprived of normal blood flow during the procedure. Once the injury develops, patients have few established treatment options besides supportive care.

Mark Okusa, MD, Joseph Gigliotti, PhD (University of Virginia), and their colleagues found that a drug-free, noninvasive, ultrasound-based treatment could prevent acute kidney injury in mice. When they exposed anesthetized mice to ultrasound with a routine clinical imaging system 24 hours prior to blood disruption to the kidneys, the mice exhibited preserved kidney health after blood flow was restored. In contrast, sham-treated mice exhibited significant kidney injury. Further analyses revealed that the ultrasound treatment likely stimulated an anti-inflammatory response that originated from the spleen and was responsible for protecting the kidneys.

"Our studies using noninvasive ultrasound now provide us with an active treatment that appears to be simple, effective, and nontoxic for the prevention of acute kidney injury," said Dr. Okusa. "To our knowledge this has never been described for the prevention of tissue or organ injury. Interestingly, we suspect that similar mechanisms that lead to kidney injury may also lead to lung, heart, and liver damage and that this form of therapy might be effective for prevention of injury in other organs as well."

In an accompanying editorial, Alain Le Moine, MD, PhD (Erasme Hospital, in Belgium) and his colleagues noted that opportunities arising from the work are numerous and promising because many procedures that carry a very high risk of AKI are planned. "In searching for novel approaches to prevent and even cure AKI, we believe that splenic ultrasound stimulation has a bright future ahead," they wrote.

The above story is based on materials provided by American Society of Nephrology.

Translate this page: Chinese French German Italian Japanese Korean Portuguese Russian Spanish

comments powered by Disqus

Related »

Acute Kidney Injury in Hospitalized Diabetic Patients Linked to Chronic Kidney Disease
Findings from a recent University of Cincinnati (UC) and Cincinnati Department of Veterans Affairs (VA) Medical Center study show …
New Research Shows Clear Association Between ACE Inhibitors And Acute Kidney Injury
Cambridge scientists have found an association between ACE inhibitors (and similar drugs) and acute kidney injury - a sudden …
Warning Signs Predict Kidney Injury After Surgery
Washington, DC (August 12, 2011) — Acute kidney injury (AKI) is a common – but preventable -- complication after …
Rapid Diagnosis of Severe Kidney Damage
How does a doctor determine whether or not an emergency-room patient has acute kidney injury? Using tests currently available …
MU Researchers Find Pet Kidney Injuries Are Similar to Human Kidney Injuries
When evaluating early kidney injuries in people, doctors monitor blood level increases of creatinine, a waste product of muscle …
Risk of Kidney Disease Doubled with Use of Fluoroquinolone Antibiotics
The risk of acute kidney disease is doubled for people taking oral fluoroquinolone antibiotics, according to a study of …
Simple Urine Test Detects Common Causes of Kidney Dysfunction After Transplantation
Washington, DC (March 6, 2014) — A new noninvasive urine test can distinguish among different causes of acute kidney …
Nephrologist Follow-up Improves Mortality of Severe Acute Kidney Injury Patients
TORONTO, April 30, 2013—Patients with acute kidney injury who see a nephrologist within 90 days of being discharged from …
Can Proteins in the Blood Predict an Early Death?
Certain measures of kidney health may predict who is likely to die prematurely, according to a study appearing in …
More » 
© Newsline Group  |  About  |  Privacy Policy  |  Feedback  |  Mobile