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Dantrolene Protects Neurons from Huntington's Disease
Published: November 25, 2011.  by  BioMed Central

Huntington's disease (HD) is characterized by ongoing destruction of specific neurons within the brain. It affects a person's ability to walk, talk, and think - leading to involuntary movement and loss of muscle co-ordination. New research published in BioMed Central's open access journal Molecular Neurodegeneration shows that the RyanR inhibitor Dantrolene is able to reduce the severity of walking and balance problems in a mouse model of HD.

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Category
Science » Biology » Cntf, Alpha-Synuclein »

Keywords
Neurons, Dantrolene, Ryanr, Muscle, Mice, Loss, Huntington, Destruction, Co-Ordination,

Cluster Centroids (Superclass Keywords)
Cntf, Alpha-Synuclein, Dantrolene, Neurons, Stat3, Tshz3, Ncmir, Erbin, Mice, Mei, Co-Ordination, Ryanr, Parafacial, Inhibitory, Boassa, Tarp, Respiratory, Birth, Gamma-2, Huntington, Colleagues, Destruction, CéZanne, DéVeloppement, Diego, Excitement, Marseille, Terminals, Synapses, Paris-Sud, Progressive, Neun, Bezprozvanny, Neun-Positive, Gaba, Excitatory, San, Neuroscience, Activity, Muscle, Releasing, Job, Involuntary, Neurotransmitter, Development, Georgia, Respiration, Newborn, Quash, Erbb4,

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