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Protein Discovery Could Switch Off Cardiovascular Disease

Published: March 12, 2012.
Released by Queen Mary, University of London  

Researchers from Queen Mary, University of London and the University of Surrey have found a protein inside blood vessels with an ability to protect the body from substances which cause cardiovascular disease. The findings, published online in the journal Cardiovascular Research, have revealed the protein protein pregnane X receptor (PXR) can switch on different protective pathways in the blood vessels.


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New Computer Program First to Recognise Sketches More Accurately Than a Human
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medicine
Common Mental Health Drug Could Be Used to Treat Arthritis
The research carried out at Queen Mary University of London (QMUL) in collaboration with scientists at the University of Otago in New Zealand, tested the effects of lithium chloride on cartilage and found that it slowed the degradation associated with osteoarthritis. Osteoarthritis results in degradation of cartilage in joints leading to pain and immobility. It currently affects a third of over 45s in the UK and there are currently no treatments that can prevent it.

technology
Most Internet Anonymity Software Leaks Users' Details
Virtual Private Networks (VPNs) are legal and increasingly popular for individuals wanting to circumvent censorship, avoid mass surveillance or access geographically limited services like Netflix and BBC iPlayer. Used by around 20 per cent of European internet users they encrypt users' internet communications, making it more difficult for people to monitor their activities.

medicine
Many Fixed-dose Drug Combinations in India Lack Central Regulatory Approval
Fixed-dose drug combinations (FDCs) which have not received central regulatory approval are sold in substantial numbers in India -- despite concerns over the safety and efficacy of these combinations -- according to new research led by Queen Mary University of London and published in PLOS Medicine.

biology
First Evolutionary History of 50 Years of Music Charts Using Big Data Analysis of Sounds
The researchers studied trends in style, the diversity of the charts, and the timing of musical revolutions. They find that, contrary to popular belief, the so-called "British Invasion" of US pop music by groups such as The Beatles and The Rolling Stones, did not start a rock revolution, but only followed existing trends. The greatest musical revolution in US pop history was also not 1964, but 1991when hip-hop arrived in the charts.

biology
Bumblebees Use Nicotine to Fight Off Parasites
Researchers from Queen Mary University of London (QMUL) and Royal Holloway, University of London (RHUL), gave bumblebees the option to choose between a sugar solution with nicotine in it and one without. Those bees infected with the Crithidia bombi parasite were more likely to go for the nicotine-laced nectar than those that weren't infected.

technology
Reducing Big Data Using Ideas from Quantum Theory Makes It Easier to Interpret
Analysing the large volumes of data gathered by modern businesses and public services is problematic. Traditionally, relationships between the different parts of a network have been represented as simple links, regardless of how many ways they can actually interact, potentially loosing precious information. Only recently a more general framework has been proposed to represent social, technological and biological systems as multilayer networks, piles of 'layers' with each one representing a different type of interaction. This approach allows a more comprehensive description of different…

medicine
Concerns over UK Government Plan to Increase Participation in School Rugby
Government plans to increase participation in rugby within schools fail to take into account data on the serious levels of school rugby-related injury and are happening in the absence of systems for injury surveillance and prevention - according to experts from Queen Mary University of London (QMUL) and published in the BMJ.

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Scientists Discover Genetic Switch That Can Prevent Peripheral Vascular Disease in Mice
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