Researchers at the University of California, San Diego School of Medicine report that a protein called beta-catenin plays a critical, and previously unappreciated, role in promoting recovery of stricken hematopoietic stem cells after radiation exposure.
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New Genetic 'Operating System' Facilitated Evolution of 'Bilateral' Animals
The evolution of worms, insects, vertebrates and other "bilateral" animals—those with distinct left and right sides—from less complex creatures like jellyfish and sea anemones with "radial" symmetry may have been facilitated by the emergence of a completely new "operating system" for controlling genetic instructions in the cell.
First Comprehensive Meshfree Numerical Simulation of Skeletal Muscle Tissue Achieved
Engineers at the University of California, San Diego, have completed the first comprehensive numerical simulation of skeletal muscle tissue using a method that uses the pixels in an image as data points for the computer simulation—a method known as mesh-free simulation.
A 'Frenemy' in Parkinson's Disease Takes to Crowdsourcing
The protein alpha-synuclein is a well-known player in Parkinson's disease and other related neurological conditions, such as dementia with Lewy bodies. Its normal functions, however, have long remained unknown. An enticing mystery, say researchers, who contend that understanding the normal is critical in resolving the abnormal.
Disease Without Borders
In a paper published this week online in Global Society, researchers with University of California, San Diego School of Medicine and the Urban Studies and Planning Program, also at UC San Diego, present a bioregional guide that merges place-based (territorial) city planning and ecosystem management along the United States-Mexico border as way to improve human and environmental health.
Program Predicts Placement of Chemical Tags That Control Gene Activity
Biochemists working at the University of California, San Diego, have developed a program that predicts the placement of chemical marks that control the activity of genes based on sequences of DNA. They describe their analysis and report results from its application to human embryonic cells in a paper published in Nature Methods online September 21.