Damage Control: Recovering from Radiation And Chemotherapy
Published: May 1, 2014.
Released by University of California - San Diego
Researchers at the University of California, San Diego School of Medicine report that a protein called beta-catenin plays a critical, and previously unappreciated, role in promoting recovery of stricken hematopoietic stem cells after radiation exposure.
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Chemists Create Modular System for Placing Proteins on Membranes
With a tag, an anchor and a cage that can be unlocked with light, chemists have devised a simple, modular system that can locate proteins at the membrane of a cell. "If you're trying to emulate the way nature does this, you need a lot of complex machinery," said Andrew Rudd, a graduate student in chemistry and biochemistry at the University of California, San Diego.
Breast Tumor Stiffness And Metastasis Risk Linked by Molecule's Movement
Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center have discovered a molecular mechanism that connects breast tissue stiffness to tumor metastasis and poor prognosis. The study, published April 20 in Nature Cell Biology, may inspire new approaches to predicting patient outcomes and halting tumor metastasis.
Overnight Fasting May Reduce Breast Cancer Risk in Women
A decrease in the amount of time spent eating and an increase in overnight fasting reduces glucose levels and may reduce the risk of breast cancer among women, report University of California, San Diego School of Medicine researchers in the journal Cancer Epidemiology, Biomarkers & Prevention. The findings were presented at the American Association of Cancer Research's annual meeting in Philadelphia.
Falsified Medicines Taint Global Supply
When you take a medication for, say, high cholesterol, do you know that pill is really what the label says it is? Depending upon the type of medicine and where you live, the threat of falsified medications (also referred to as counterfeit, fraudulent, and substandard) can be quite real, yet the full scope and prevalence of the problem is poorly understood, say researchers at University of California, San Diego School of Medicine in a new report published April 20 in the American Journal
Artificial Blood Vessel Lets Researchers Better Assess Clot Removal Devices
Researchers at the University of California, San Diego School of Medicine have created an in vitro, live-cell artificial vessel that can be used to study both the application and effects of devices used to extract life-threatening blood clots in the brain. The artificial vessel could have significant implications for future development of endovascular technologies, including reducing the need for animal models to test new devices or approaches.
Genetics Overlap Found Between Alzheimer's Disease And Cardiovascular Risk Factors
An international team of scientists, led by researchers at University of California, San Diego School of Medicine, have found genetic overlap between Alzheimer's disease (AD) and two significant cardiovascular disease risk factors: high levels of inflammatory C-reactive protein (CRP) and plasma lipids or fats. The findings, based upon genome-wide association studies involving hundreds of thousands of individuals, suggest the two cardiovascular phenotypes play a role in AD risk - and perhaps offer a new avenue for potentially delaying disease progression.
Engineers Elucidate Why Skin Is Resistant to Tearing
Skin is remarkably resistant to tearing and a team of researchers from the University of California, San Diego and the Lawrence Berkeley National Laboratory now have shown why.
Golgi Trafficking Controlled by G-proteins
A family of proteins called G proteins are a recognized component of the communication system the human body uses to sense hormones and other chemicals in the bloodstream and to send messages to cells. In work that further illuminates how cells work, researchers at University of California, San Diego School of Medicine have discovered a new role for G proteins that may have relevance to halting solid tumor cancer metastasis. The study is reported online April 9 in Developmental Cell.
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