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Damage Control: Recovering from Radiation And Chemotherapy

Published: May 1, 2014.
By University of California - San Diego
http://www.ucsd.edu

Researchers at the University of California, San Diego School of Medicine report that a protein called beta-catenin plays a critical, and previously unappreciated, role in promoting recovery of stricken hematopoietic stem cells after radiation exposure.


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medicine
A Better Way to Track Emerging Cell Therapies Using MRIs
Cellular therapeutics – using intact cells to treat and cure disease – is a hugely promising new approach in medicine but it is hindered by the inability of doctors and scientists to effectively track the movements, destination and persistence of these cells in patients without resorting to invasive procedures, like tissue sampling.
technology
Engineers Develop Algorithms to Switch Out And Recharge Battery Modules in Electric Cars
Imagine being able to switch out the batteries in electric cars just like you switch out batteries in a photo camera or flashlight. A team of engineers at the University of California, San Diego, are trying to accomplish just that, in partnership with a local San Diego engineering company.
medicine
Cancer And the Immune System: A Double-edged Sword
During cancer development, tumor cells decorate their surfaces with sugar compounds called glycans that are different from those found on normal, healthy cells. In the Sept. 15 online Early Edition of the Proceedings of the National Academy of Sciences (PNAS), researchers at the University of California, San Diego School of Medicine report that sialic acids at the tips of these cancer cell glycans are capable of engaging with immune system cells and changing the latter's response to the tumor – for good and…
medicine
Scientists Discover Neurochemical Imbalance in Schizophrenia
Using human induced pluripotent stem cells (hiPSCs), researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California, San Diego have discovered that neurons from patients with schizophrenia secrete higher amounts of three neurotransmitters broadly implicated in a range of psychiatric disorders.
technology
Video Game Teaches Kids How to Code
Computer scientists at the University of California, San Diego have successfully funded on Kickstarter a new and improved version of CodeSpells, a first-person player game they developed that teaches players how to code.
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Growth Factor Aids Stem Cell Regeneration After Radiation Damage
By Duke University Medical Center
DURHAM, N.C. – Epidermal growth factor has been found to speed the recovery of blood-making stem cells after exposure to radiation, according to Duke Medicine researchers. The finding could …
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Gene Therapy Breakthrough Heralds Treatment for Beta-thalassemia
By Wiley-Blackwell
Italian scientists pioneering a new gene transfer treatment for the blood disorder β-thalassemia have successfully completed preclinical trials, claiming they can correct the lack of beta-globin (ß-globin) in patients' …
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Stem Cell Discovery Could Lead to Improved Bone Marrow Transplants
By University of California - Santa Cruz
SANTA CRUZ, CA--Researchers at the University of California, Santa Cruz, have identified a key molecule for establishing blood stem cells in their niche within the bone marrow. The findings, …
Cells 
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Gene Therapy Breakthrough Heralds Treatment for β-thalassemia
By Wiley - Blackwell
Italian scientists pioneering a new gene transfer treatment for the blood disorder β-thalassemia have successfully completed preclinical trials, claiming they can correct the lack of beta-globin (ß-globin) in patients' …
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12/5/12 
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Studying Marrow, URMC Researchers Accelerate Blood Stem Cells
By University of Rochester Medical Center
University of Rochester Medical Center scientists are testing a new approach to speed a patient's recovery of blood counts during a vulnerable period after a stem-cell transplant, according to …
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Keeping Stem Cells Strong
By California Institute of Technology
When infections occur in the body, stem cells in the blood often jump into action by multiplying and differentiating into mature immune cells that can fight off illness. But …
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Unappreciated Dynamism of Blood Cell Production
By Rockefeller University Press
The bone marrow stem cells responsible for generating new blood cells are less fixed and more flexible than previously thought, according to a paper published online on February 7 …
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5/12/11 
Study Reveals Origins of a Cancer Affecting the Blood And Bone Marrow
By NYU Langone Medical Center / New York University School of Medicine
A new study by the NYU Cancer Institute, an NCI-designated cancer center, sheds light on the origins of myeloid leukemia, a type of blood cancer that affects children and …
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DNA-altering Enzyme Is Essential for Blood Cell Development
By Journal of Clinical Investigation
The expression of specific genes is partially dictated by the way the DNA is packed into chromatin, a tightly packed combination of DNA and proteins known as histones. HDAC3 …
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