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Damage Control: Recovering from Radiation And Chemotherapy

Published: May 1, 2014.
By University of California - San Diego
http://www.ucsd.edu

Researchers at the University of California, San Diego School of Medicine report that a protein called beta-catenin plays a critical, and previously unappreciated, role in promoting recovery of stricken hematopoietic stem cells after radiation exposure.


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More news from University of California - San Diego


medicine
Enzyme Controlling Metastasis of Breast Cancer Identified
Researchers at the University of California, San Diego School of Medicine have identified an enzyme that controls the spread of breast cancer. The findings, reported in the current issue of PNAS, offer hope for the leading cause of breast cancer mortality worldwide. An estimated 40,000 women in America will die of breast cancer in 2014, according to the American Cancer Society.
medicine
Fear, Safety And the Role of Sleep in Human PTSD
The effectiveness of post-traumatic stress disorder (PTSD) treatment may hinge significantly upon sleep quality, report researchers at the University of California, San Diego School of Medicine and Veterans Affairs San Diego Healthcare System in a paper published today in the Journal of Neuroscience.
medicine
Finding Keys to Glioblastoma Therapeutic Resistance
Researchers at the University of California, San Diego School of Medicine have found one of the keys to why certain glioblastomas – the primary form of a deadly brain cancer – are resistant to drug therapy. The answer lies not in the DNA sequence of the tumor, but in its epigenetic signature. These findings have been published online as a priority report in the journal Oncotarget.
nature
Severe Drought Is Causing the Western US to Rise
The severe drought gripping the western United States in recent years is changing the landscape well beyond localized effects of water restrictions and browning lawns. Scientists at Scripps Institution of Oceanography at UC San Diego have now discovered that the growing, broad-scale loss of water is causing the entire western U.S. to rise up like an uncoiled spring.
technology
Researchers Find Security Flaws in Backscatter X-ray Scanners
A team of researchers from the University of California, San Diego, the University of Michigan, and Johns Hopkins University have discovered several security vulnerabilities in full-body backscatter X-ray scanners deployed to U.S. airports between 2009 and 2013.
Related »

Bone 
7/29/13 
Could Sleeping Stem Cells Hold Key to Treatment of Aggressive Blood Cancer?
By Queen Mary, University of London
Scientists studying an aggressive form of leukaemia have discovered that rather than displacing healthy stem cells in the bone marrow as previously believed, the cancer is putting them to …
Radiation 
2/3/13 
Growth Factor Aids Stem Cell Regeneration After Radiation Damage
By Duke University Medical Center
DURHAM, N.C. – Epidermal growth factor has been found to speed the recovery of blood-making stem cells after exposure to radiation, according to Duke Medicine researchers. The finding could …
Marrow 
1/31/13 
Diabetes Distresses Bone Marrow Stem Cells by Damaging Their Microenvironment
By University of Bristol
New research has shown the presence of a disease affecting small blood vessels, known as microangiopathy, in the bone marrow of diabetic patients. While it is well known that …
Blood 
10/23/12 
Duke Research Team Identifies a Potent Growth Factor for Blood Stem Cells
By Duke University Medical Center
DURHAM -- Duke Medicine researchers studying the interaction of blood stem cells and the niche where they reside have identified a protein that may be a long-sought growth factor …
Cells 
3/1/11 
How Long Do Stem Cells Live?
By Sanford-Burnham Medical Research Institute
LA JOLLA, Calif., March 1, 2011 – When patients receive a bone marrow transplant, they are getting a new population of hematopoietic stem cells. Fresh stem cells are needed …
Infection 
6/9/10 
Gamma Interferon a Wake-up Call for Stem Cell Response to Infection
By Baylor College of Medicine
HOUSTON -- (June 10, 2010) – Most of the time, the body's blood-forming (hematopoietic) stem cells remain dormant, with just a few producing blood cells and maintaining a balance …
Cells 
10/22/12 
★★★★ 
Stem Cell Bodyguards
By Weizmann Institute of Science
Hiding deep inside the bone marrow are special cells. They wait patiently for the hour of need, at which point these blood forming stem cells can proliferate and differentiate …
Stem 
6/28/13 
Type 2 Diabetes Patients Transplanted with Own Bone Marrow Stem Cells Reduces Insulin Use
By Cell Transplantation Center of Excellence for Aging and Brain Repair
Putnam Valley, NY. (June 28 2013) –A study carried out in India examining the safety and efficacy of self-donated (autologous), transplanted bone marrow stem cells in patients with type …
Cells 
10/3/12 
Cedars-Sinai Study Sheds Light on Bone Marrow Stem Cell Therapy for Pancreatic Recovery
By Cedars-Sinai Medical Center
LOS ANGELES (Oct. 2, 2012) – Researchers at Cedars-Sinai's Maxine Dunitz Neurosurgical Institute have found that a blood vessel-building gene boosts the ability of human bone marrow stem cells …
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